VDAC1 and non-small cell lung carcinoma: As a corollary, reducing VDAC1 expression with siRNA negated cisplatin-induced apoptosis and Bax activation in non-small cell lung cancer (NSCLC) cells [150], reduced apoptosis induced by endostatin [151], and inhibited selenite-induced permeability transition pore (PTP) opening in HeLa cells [152].