GJA1 and ischemia: The results showed a significant decrease in the viability of primary astrocyte cultures in the “ischemia” group (see Supplementary Materials 1, Supplementary Materials Table S1), whereas blockage of Cx43 during ischemia modeling maintained the viability of astrocytes at the intact culture level (“control” 98.25 [96.99; 99.197]%, “ischemia” 95.59 [94.55; 97.35]%, “ischemia+Gap19” 99.21 [97.61; 100.0]%).