Unlike cutaneous melanoma, which is characterized by a UV signature, MM harbors distinct molecular features, including a lower incidence of v-Raf murine sarcoma viral oncogene homolog B (BRAF) oncogene mutations but a higher incidence of tyrosine-protein kinase KIT (CD117) oncogene mutations, suggesting different genetic etiologies. Here, BRAF is linked to Miyoshi myopathy.