IL6 and COVID-19: COVID-19 is usually accompanied by an elevation of numerous bioactive factors such as IL-1β, TNF-α, IL-2, IL-7, IL-8, IL-9, IL-17 G-CSF, interferon (IFN)-γ, XXC-10, CCL-2 CCL-3, CCL-4, and especially IL-6, which is produced predominantly by macrophages [110,111].