Upregulation of EGR1, EGR2, and EGR3 occurred in ME/CFS patients with a raised level of EBI2 mRNA (Figure 1), suggesting that expression of these four genes in PBMC of ME/CFS patients was linked with EBV infection/reactivation (see below). The gene discussed is EGR3; the disease is myalgic encephalomeyelitis/chronic fatigue syndrome.