In another study, oral administration of 200 mg/Kg b.w. BCP to STZ-induced diabetic rats significantly improved the levels of antioxidant enzymes, decreased lipid peroxidative markers in plasma and pancreatic tissues and reversed proinflammatory cytokines (TNF-α and IL-6) to near normal levels, thus indicating a relevant anti-inflammatory role of BCP in preventing diabetes-induced oxidative stress and associated complications [139]. This evidence concerns the gene TNF and diabetes mellitus.