Similarly, older cases had higher p16INK4a mRNA expression than younger cases (5.79 vs. 2.99, p < 0.001), Black cases had statistically significantly higher p16INK4a mRNA expression than their White counterparts (5.18 vs. 4.22, p = 0.013), and cases with family history of cancer had higher p16INK4a mRNA expression than those without (5.86 vs. 4.29, p < 0.001). The gene discussed is CDKN2A; the disease is cancer.