In turn, Zang et al. (2013, 2014) suggests that non-tumor-associated forms of p53 inhibit the translocation of glucose transporters (GLUT1, GLUT4) to the plasma membranes, overexpression RRAD (Ras-related associated with diabetes), which impairs glucose uptake and results in insulin resistance in muscle and adipose tissues [35,36]. This evidence concerns the gene TP53 and neoplasm.