NFAT5 and Duchenne muscular dystrophy: In DMD fibroblasts, where NFAT5 seems mainly located in the nucleus, this phenomenon could not occur by the absence of communication between p38-MAPK and NFAT5, thereby bypassing a possible natural anti-fibrosis mechanism, and partially explaining the permanent fibrotic tissue production and deposition seen in DMD, which is harmful to patients.