CCL2 and rheumatoid arthritis: In a study by Nakamachi et al., decreased expression of hsa-miR-124 was observed in fibroblast like synoviocytes (FLS) of patients with RA where hsa-miR-124a contributed to the inflammatory processes in RA pathogenesis by targeting the monocyte chemoattractant protein-1 (MCP-1) and cyclin-dependent kinase-2 (CDK-2) [62].