Lactate stimulates the expression of its own receptor [69,70] and, maybe, because of that, high expression of HCAR1 has been detected in pancreatic tumors [71], in breast cancer [72,73] and in cell lines from colon, breast, lung, hepatocellular, salivary gland, cervical, and pancreatic carcinomas [71,72,73,74]. This evidence concerns the gene HCAR1 and pancreatic neoplasm.