MKI67 and colorectal carcinoma: We identified a significant difference in the proliferation status of ILS/ELS, measured by the magnitude of Ki67-positive cells, between NT and CRC as well as NT and CRCLM (p = 0.014 and p < 0.001, respectively), with the highest proliferation activity of immune cells located in the ILS within NT (median 5.40%, ranging from 1.28% to 20.71%).