C3AR1 and cancer: This study is in line with previous observations of an abnormal expression of complement proteins in different type of cancer, especially C1 complex [23], C3 [24], C4 [25], C5 [24], C3aR [24], C5aR1 [24], FB [26], FH [27], FI [28], CD46 [29], CD55 [30], CD59 [30].