CASP3 and breast carcinoma: EGCG has shown that the induction of cell death by increasing apoptosis-related proteins, such as caspase-3, caspase8, caspase9, Fas, cytochrome c, PTEN, bad, and smac, suppressed the antiapoptotic proteins B-cell leukemia/lymphoma-2 protein (Bcl-2), bcl-xL, and c-myc in 4T1 breast cancer cells [49].