Based on bibliographic data, tissue pattern of expression, biological function of the encoded protein, and a catalog of somatic mutations, we narrowed down the list to five variants in five different genes which may be implicated either in the pathogenesis of PCC (KLHL7 and PKM) or sarcomas (RIPK3, TMEM214 and TFAP2E). The gene discussed is TMEM214; the disease is adrenal gland pheochromocytoma.