Curras-Freixes et al. (8) reported three germline variants of unknown significance (VUS) of KIF1B in their cohort of PCC patients, representing a prevalence of 0.66% (3/453) in line with our own estimation of the prevalence of KIF1B VUS at 1.3% (1/74 patients with PCC/PGL analyzed by NGS between 2017 and 2019, unpublished data). This evidence concerns the gene KIF1B and adrenal gland pheochromocytoma.