CASP8 and breast cancer: None of the other investigated SNPs showed any association with BC in Jordanian patients, but, upon the application of the dominant model (homozygote dominant GG vs heterozygote GA + recessive homozygote AA), the rs6760993 SNP of the CASP8 gene showed association with the disease (p-value = 0.04).This finding reveal an involvement of the dominant genotype GG of CASP8 gene variant rs6760993 with BC risk.