A total of 508 men who were diagnosed with prostate cancer between 1986 and 2018 were included in the study (median [range] age, 61 [37-88 ] years; baseline median [range] PSA level, 18.5 ng/mL [0.7-7577 ng/mL] [to convert to micrograms per liter, multiply by 1.0]). The gene discussed is KLK3; the disease is prostate cancer.