In our work, we found that serum VEGF, bFGF, and IL‐6, which are associated with tumor growth and progression,25, 27 were increased (Figure 5G‐H and J) and IL‐1a, which promotes antitumor immune effects,26 and was lower in BALB/c nude mice bearing 4T1 after chronic stress (Figure 5I). Here, FGF2 is linked to neoplasm.