TP53 and melanoma: Within the differential processes of KPF involved in its antiproliferative and proapoptotic-like effects against G. duodenalis trophozoites as compared to mammalian models was the absence of oxidative stress, i.e., the absence of ROS production, in contrast to the activated ROS-p38MAPK-p53 axis that precedes apoptosis in malignant melanoma and colorectal cells.24