In AML (acute myelogenous leukemia) patients, the ratio of four major WT1 isoforms A : B : C : D was shown as 17 : 23 : 24 : 31% while the ratio of these isoforms was 10 : 16 : 7 : 39% in normal CD34+ cells. The gene discussed is CD34; the disease is acute myeloid leukemia.