In addition, BDNF is known to protect neuronal cells against oxidative stress (Shin et al., 2019).Although LBP decreases anxiety levels by changing antioxidant biomarkers (Zhao et al., 2015), it is unknown whether or not the anxiolytic effects of LBP on ovariectomized rats are caused by increasing hippocampal SERs. Here, BDNF is linked to Anxiety.