The results showed that intermittent fasting from dawn to sunset for more than 14 h daily for four consecutive weeks induced a unique anticancer, anti-diabetes and anti-aging proteomic response (Table 2, Figs. 1 and 2), upregulated several regulatory proteins that play a key role in tumor suppression, DNA repair, humoral defense, insulin signaling, and downregulated several tumor promotor proteins. This evidence concerns the gene INS and diabetes mellitus.