Most of the genes for chemokines/chemokine receptors (CCR2, CCR6, CCR7, CSF2RB, CX3CR1 and CXCR4) and cytokines/cytokines receptors (IL1R2, IL8, IL18, IL20RA and IL22RA2) were down-regulated after infection by vvIBDV at 3 dpi. This evidence concerns the gene CXCL8 and infection.