Regarding functional liver reserve, presence of pre-sarcopenia was significantly associated with prolonged prothrombin time (international normalized ratio [INR]: 1.15 vs. 1.09, p = 0.001), lower serum albumin level (3.2 vs. 3.4 g/dL, p = 0.011), and a higher incidence of ascites formation (49.2% vs. 39.7%, p = 0.018). The gene discussed is ALB; the disease is Ascites.