RBM20 and familial dilated cardiomyopathy: Third, the subcellular localization of RBM20 proteins has not been investigated in patients with clinical DCM, with and without a mutation in RBM20. To evaluate the relevance of the granule-like structures in Rbm20S637A/S637A mice with the DCM phenotypes of the patients, further experiments using human biopsy samples or cardiomyocytes differentiated from patient-derived induced pluripotent stem cells (iPSCs) are necessary.