Through GSEA, we found that the high-risk-score group had enrichment in KEGG pathways related to metabolism (Fig. 8): the hedgehog signaling pathway, the TGF-β signaling pathway and a pathway related to arrhythmogenic right ventricular cardiomyopathy (ARVC). The gene discussed is TGFB1; the disease is arrhythmogenic right ventricular cardiomyopathy.