VAV3 and osteosarcoma: In this paper, using a bioinformatics analysis, we found that LINC00265, spermidine/spermine N1-acetyltransferase-1 (SAT1) and vav guanine nucleotide exchange factor 3 (VAV3) were overexpressed in osteosarcoma, showed a positive correlation with osteosarcoma, and were associated with a poor prognosis in osteosarcoma patients.