We speculate that the higher rate of EBV infection in CHAF1B-depleted cells may have resulted from increased expression of the EBV coreceptor major histocompatibility complex (MHC) class II (Table S1), including a 4-fold increase in HLA-DP, a 3-fold increase in HLA-DRA, a 2-fold increase in HLA-DMA, a 1.7-fold increase in HLA-DPB1, and significant increases in transcripts of the MHC class II pathway regulators HLA-DM and HLA-DO. Here, HLA-DMA is linked to Epstein-Barr virus infection.