WT BMDMs had increased secretion of IL-18 following infection with C. albicans or A. fumigatus (Fig. 3D, Fig. S3B), whereas the Zbp1–/– and Zbp1ΔZα2/ΔZα2 BMDMs had significantly reduced IL-18 release compared with the WT (Fig. 3D, Fig. S3B). The gene discussed is IL18; the disease is infection.