Moreover, the ALI + oe-PRDM1 group demonstrated decreased ratio of lung W/D (Fig. 5D), decreased MPO activity (Fig. 5E), and expression levels of inflammatory factor TNFα, IL-6, and IL-1β in BALF (Fig. 5F) compared with the ALI + oe-NC group. This evidence concerns the gene IL1B and acute respiratory distress syndrome.