MPO and acute respiratory distress syndrome: We found that lung injury was increased in the ALI mouse models as evidenced by up-regulated W/D ratio, MPO activity and the concentration of TNFα, IL-6, and IL-1β, while the infiltration of inflammatory cells was reduced in the lung tissues, whereas all the aforementioned could be countered by the addition of miR-99b antagomir, which is very much in line with the previous data.