To verify the overexpression of miR-375 curtailed MELK to inhibit cervical cancer cell proliferation, migration, and invasion in cervical cancer cells, the C33A cells were transfected with sh-NC, sh-MELK, both miR-375 mimic and NC-Vector, or both miR-375 mimic and MELK-Vector. The gene discussed is MELK; the disease is cervical cancer.