AKT1 and cancer: The greatest number and diversity of pQTL targets (n = 16) was observed for rs681343, including BPIFB1, which plays a role in antimicrobial response in oral and nasal mucosa [45]; FUT3, which catalyzes the last step of Lewis antigen biosynthesis; and FGF19, part of the PI3K/Akt/MAPK signaling cascade that is dysregulated in cancer and neurodegenerative diseases [46].