These observations are consistent with the established role the HLA region, including HLA-DQB1, in schizophrenia etiology [104, 105], and is further supported by previously reported associations for rs9273325 with blood cell traits [62] and immunoglobulin A deficiency [106], as well as its role as an eQTL for HLA-DQB1 in CD4+ T2h cells. Here, HLA-DQB1 is linked to selective IgA deficiency disease.