UBE2CP3, which is highly expressed in hepatocellular carcinoma tissues, promotes human umbilical vein endothelial cell (HUVEC) proliferation, migration, and tube formation through the ERK/HIF-1/p70S6K/VEGFA axis in vitro and in vivo compared to paracancer tissues, leading to upregulation of VEGFA expression [289]. Here, HIF1A is linked to hepatocellular carcinoma.