Specifically, we identified 18 independent HIV-specific loci associated with HDL, 11 with LDL, and seven with triglyceride levels in PLWHAA at p < E−5, including intergenic variants in CPA6, previously associated with total cholesterol [57] and T2D [58] in individuals of African ancestry, and PRKG1 linked to body composition [59]. This evidence concerns the gene CPA6 and type 2 diabetes mellitus.