Immunohistochemical analysis of EMT markers E-cadherin and Vimentin in the tumor sections of nude mice receiving intraperitoneal injection of control and RAGE shRNA treated A549, MDA MB-231 and MCF-7 cells and treated with LPA revealed higher expression of epithelial maker E-cadherin in untreated ones than the LPA treated nude mice. The gene discussed is AGER; the disease is neoplasm.