Furthermore, the Kaplan-Meier survival curves demonstrated that patients with high JARID1B expression levels in 130 immunohistochemical results had a significantly poorer overall survival than those with low expression levels (Fig. 1f), while univariate and multivariate analysis of overall survival in CRC patients also indicated that high JARID1B expression was a risk factor for 5-year survival (Table 2). This evidence concerns the gene KDM5B and colorectal carcinoma.