Circ‐ZFR causes cell cycle arrest and apoptosis of GC through sponging miR‐107/miR‐130a, which binds to the 3ʹ untranslated region (UTR) of PTEN. 52Many studies have shown that PTEN can be targeted and regulated by miR‐107 and miR‐130a, affecting the activity of cancer cells.53, 54. This evidence concerns the gene PTEN and cancer.