Following the finding that AS reduced diabetes‐induced inflammation, we went on to further investigate the role of NLRP3 (NOD‐like receptor family, pyrin domain containing 3) inflammasome in this pathology, given that NLRP3 has emerged as a central regulator in the inflammatory process that contributes to the aggravation of DM and diabetic complications.34 The gene discussed is NLRP3; the disease is diabetes mellitus.