Here, we replicated our previous digital pathologic data18 in a largely non‐overlapping dataset using open‐source digital image analysis tools and found greater relative tau neuropathology in the STC compared to other regions in LBD+AD, while Aβ regional severity was more diffuse (Table 6) emphasizing the regional specificity of tau pathology and resultant neurodegeneration in LBD. The gene discussed is MAPT; the disease is Alzheimer disease.