RHO and Huntington disease: We used kinome analysis (Berard et al. 2018) to screen for potential phosphorylation events (Jalal et al. 2009) and identified several affected signaling cascades, including the Rho-Rac GTPase cascade that has been associated with cytoskeletal phenotypes in various models of HD (Puigdellivol et al. 2015; Tourette et al. 2014; Tousley et al. 2019).