Notably, MIP‐1α and MIP‐1β elevated by OLP T‐exos may in turn attract mononuclear cells and recruit CD8+ T lymphocytes via CCR1 and CCR5, indicating that OLP T‐exos might contribute to the development of OLP by increasing the infiltration of T lymphocytes in lesional sites. Here, CCR5 is linked to oral lichen planus.