TMPRSS11D and amyotrophic lateral sclerosis: Increasing Tip60 HAT activity partially restored STM in the PD (Fig. 6F: F(2,6) = 26.63, p = 0.0010, one-way ANOVA with Tukey’s post hoc analysis) while there was a non-significant trend in rescue in HD larvae (Fig. 6D) and in ALS larvae (Fig. 6G).