The mRNA level of C-C motif chemokine ligand 2 (Ccl2, encoding MCP-1) and Matrix metalloproteinase 3 (Mmp3) were significantly increased only in HF + PA-fed mice but not in HF + LA-fed mice compared to CD controls (p < 0.001) (Figure 3B,C). The gene discussed is MMP3; the disease is hydrops fetalis.