As also LRRK2 can modulate the risk of inflammatory diseases such as SLE [52,53] and neuroinflammation is increased in 12-month old BAC G2019S mice (Figure 5), future studies should be directed at exploring the possible link between LRRK2 and PPM1H in PD-related inflammation. This evidence concerns the gene PPM1H and systemic lupus erythematosus.