TGFB1 and cancer: While it is possible that multiple components of H. polygyrus-derived antigens may alter cancer cell behavior in a number of ways, proteomics analysis of these antigens, combined with sequencing of the H. polygyrus genome, has led to the identification of several immunomodulatory molecules, including a structurally distinct equivalent of the mammalian transforming growth factor (TGF)-β cytokine, termed H. polygyrus TGF-β Mimic (Hp-TGM) [49,55].