As a result, CD4+ T cell response induced by oral administration of Ocs-P displays a high degree of multifunctionality with increased CD107a+IFN-γ+IL-2+TNF-α+ (up to 1.5-fold), CD107a+IFN-γ+IL-2+ (up to 1.4-fold)-, CD107a+IFN-γ+TNF-α+ (up to 1.7-fold)-, CD107a+IFN-γ+ (up to 1.6-fold)-, and IFN-γ+TNF-α+ (up to 1.3-fold)-producing T cells compared with the PBS-administered tumor-bearing group (Figure 6B). Here, IL2 is linked to neoplasm.