TNF and neoplasm: Thereafter, when CD8+ T cell responses were analyzed, Ocs-P-administered tumor-bearing group showed higher frequencies of CD107a+IFN-γ+IL-2+TNF-α+ (up to 1.7-fold), CD107a+IL-2+TNF-α+ (up to 1.6-fold)-, CD107a+IFN-γ+TNF-α+ (up to 1.7-fold)-, CD107a+IFN-γ+ (up to 1.8-fold)-, and CD107a+TNF-α+ (up to 1.8-fold)-producing T cells compared with the PBS-administered tumor-bearing group (Figure 7B).