With clinical trials investigating LNA anti-miRs, TargomiRs and liposomal packaged miRNAs designed to target various oncomiRs in solid tumors beginning to recruit, and initial reports showing relatively good safety profiles, this approach could be readily applied to multiple cancer types with PTEN deficiency in the near future, including prostate cancer [123,125,126,127]. The gene discussed is PTEN; the disease is prostate cancer.