IGHE and Allergy: We performed the following assessments: complete blood count (CBC), comprehensive metabolic profile (CMP), C-reactive protein (CRP), erythrocyte sedimentation rate (ESR), hormone levels (thyroid functions, DHEA/cortisol, pregnenolone), antigliadin antibody/tissue transglutaminase (TTG), IgE food allergy panel, immunoglobulin levels and subclasses, mineral levels (magnesium, copper, zinc), streptococcal titers (anti-streptomycin O (ASO), anti-DNase), viral titers (herpesvirus 6 (HHV-6), Epstein–Barr virus (EBV), cytomegalovirus (CMV)), Stachybotrys titer, urinalysis, and EKG.