A recent study cited six genes related to splicing that have mutations in patients with RP including PRPF31, PRPF8, PRPF3, PAP-1, SNRNP200, and PRPF6. These mutations are responsible for autosomal dominant RP in more than 12% of cases [33]. The gene discussed is PRPF3; the disease is retinitis pigmentosa 1.