TMEM37 and infection: In B. bassiana, essential roles of both ena1a and ena2b in normal host infection and insect pathogenicity are well indicated by an uncomputable LT50 for their deletion mutants against the model insect via normal cuticle infection, a loss of their ability to grow out of cadaver surfaces by cuticular penetration, and great reductions in total ECE and Pr1 activities critial for cuticle degradation [38,39].